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Tirzepatide
Tirzepatide is a dual incretin receptor agonist composed of 39 amino acids. It activates both GLP-1 and GIP receptors, thereby enhancing glucose-dependent insulin secretion, suppressing glucagon, delaying gastric emptying, and reducing appetite. With a half-life of approximately 5 days, it is convenient to administer via a once-weekly subcutaneous injection. Clinical trials have demonstrated that tirzepatide offers superior efficacy in terms of glycemic control and weight loss compared to selective GLP-1 receptor agonists.
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